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Wednesday, September 14, 2011

CSCAMM Seminar: Prof. Danny Barash - Computational Studies of RNA Switches

Recent discoveries about various capabilities of small RNAs to affect gene expression have led to some biotechnological advances and medical applications. After a brief overview of these discoveries, we will focus on the phenomenon of RNA conformational switching and how it relates to function. The computational methods that are involved in RNA folding prediction, RNA mutational analysis, and the design and search for novel RNA switches will be described. A representation of the RNA secondary structure by a Laplacian matrix and how its spectral decomposition can assist in detecting conformational rearrangements will also be discussed. {Will appear in FYI on Sep 14, 2011
Start Time:
2:00 PM
End Time:
3:00 PM
Common Location Name:
Computer Science Instructional Center
Web Address:
Other Contact Information:
Valerie Lum CSCAMM +1 301 405 0652

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