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Tuesday, September 11, 2012

Physics Colloquium: Single Molecule Experiments Reveal the Role of that Energy Landscapes Play in Biological Processes

In biology, the energy of a protein or nucleic acid molecule as a function of its physical conformation is of critical importance. It controls the folding of proteins into their native, active conformations, and it determines how much work processive enzymes must do in order to access information stored in DNA or RNA sequences. Arthur La Porta, UMD, will describe a new technique they have developed for measuring the energy of a DNA or RNA molecule as a function of its extension using an optical trap. He will describe a theoretical framework they have developed for relating the energy as a function of extension to the energy as a function of conformation, which is more directly related to biological function. Finally, he will describe what they have learned by applying this technique to several important biological systems. Full abstract at: {Will appear in FYI on Sep 11, 2012
Start Time:
4:00 PM
End Time:
5:00 PM
Common Location Name:
Web Address:
Other Contact Information:
Carole Cuaresma Kiger +1 301 405 5945

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